Presentation of immune-complexed antigens to autoreactive T cells |
Expression of adhesion and other costimulatory molecules that promote T cell activation |
Synthesis of chemokines that induce leukocyte infiltration |
Production of factors that initiate and sustain angiogenesis and granulation tissue formation |
Release of autoantibodies that are directly or indirectly (via immune complex formation) destructive to tissues |
Maintenance of a memory response to autoantigens |