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Table 4 Quantitative trait loci (QTL) associated with BMD or osteoporosis

From: Genetic markers of osteoarticular disorders: facts and hopes

  

Genetic

 

Reference

QTL

analysis

Phenotype

[135]

11q12?13

Linkage

High bone mass

[129]

1p36

  
 

2p23?24

  
 

4qter

  
 

11q

Linkage

Low BMD

[128]

11q12?13

Sib-pairs

Femoral neck BMD

[130]

2p

  
 

13q

Sib-pairs

Proximal and distal forearm BMD

[134]

1q21?23

Sib-pairs

Lumbar or femoral BMD

 

5q33?35

  
 

6p11?12

  
 

11q12?13

  
  1. BMD = bone mineral density.