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Table 2 Adipokines in lean, overweight and obese patients

From: Exercise and obesity in fibromyalgia: beneficial roles of IGF-1 and resistin?

  Lean (group 1) Overweight (group 2) Obese (group 3) Comparison of groups
  Baseline ∆15 wks ∆30 wks Baseline ∆15 wks ∆30 wks Baseline ∆15 wks ∆30 wks Groups At baseline Change after 15 weeks Change after 30 weeks
  Median (range) Median (range)
P -valuea
Median (range)
P -valuea
Median (range) Median (range)
P -valuea
Median (range)
P -valuea
Median (range) Median (range)
P -valuea
Median (range)
P -valuea
  P -valueb P -valueb P -valueb
Adipo-nectin
ng/ml
18620.8 (5707.0 to 23038.0) 783.3
(-3501.6 to 4270.7)
488.5 (-1047.7 to 6069.1) 4580.4 (2939.7 to 9634.0) 400.0
(-438.0 to 1681.0)
578.0
(-1764.5 to 1281.3)
4745.5 (2864.9 to 5879.0) 1011.3
(-382.6 to 3273.8)
1206.9
(-1157.4 to 3811.5)
Lean vs overweight 0.013 0.591 0.346
  n = 9 P = 0.441
n = 9
P = 0.398
n = 7
n = 26 P = 0.122
n = 25
P = 0.861
n = 25
n = 13 P = 0.133
n = 13
P = 0.214
n = 9
Lean vs obese 0.003 0.794 1.000
Leptin
ng/ml
16012.4 (10250.4 to 25627.3) 2136.2
(-4133.4 to 5400.4)
-4455.8 (-10473.7 to 2250.7) 27658.2 (19222.8 to 45504.1) 1417.0
(-6055.4 to 6858.3)
1760
(-9912.1 to 9778.1)
45300.0 (34456.5 to 86307.4) 5269.7
(-5534.8 to 9055.5)
1446.4
(-3059.4 to 8129.1)
Lean vs overweight 0.067 0.939 0.161
  n = 9 P = 0.515
n = 9
P = 0.128
n = 7
n = 26 P = 0.778
n = 25
P = 0.443
n = 25
n = 13 P = 0.422
n = 13
P = 0.594
n = 9
Lean vs obese <0.001 0.471 0.142
NPY
pg/ml
114.5 (86.6 to 624.6) 19.0
(-10.7 to 98.5)
6.7 122.8 (80.5 to 164.9) -7.7
(-27.4 to 31.3)
9.0 (-8.2 to 27.3) 113.7 (76.0 to 553.8) 21.8 (1.3 to 225.0) 44.4 (18.3 to 1272.7) Lean vs overweight 0.82 0.178 0.824
  n = 4 P = 0.465
n = 4
P = 0.18
n = 2
n = 16 P = 0.959
n = 16
P = 0.256
n = 15
n = 6 P = 0.075
n = 6
P = 0.043
n = 5
Lean vs obese 0.914 0.762 0.095
Resistin
pg/ml
14768.2 (12312.3 to 27191.5) 927.7
(-3165.5 to 3897.5)
1006.1
(-8555.9 to 4448.6)
14419.1 (13786.6 to 16531.2) 437.3
(-1698.2 to 2634.9)
701.1
(-573.9 to 3872.6)
14951.6 (12671.2 to 20016.0) 1189.2
(-1110.2 to 2292.4)
3110.7
(-534.1 to 4311.0)
Lean vs overweight 0.67 1.000 0.789
  n = 9 P = 0.678
n = 9
P = 1.000
n = 7
n = 26 P = 0.465
n = 23
P = 0.051
n = 25
n = 13 P = 0.221
n = 13
P = 0.214
n = 9
Lean vs obese 0.794 0.845 0.837
  1. Serum levels of adiponectin, leptin, NPY and resistin at baseline (0 weeks), change (∆) during training (15 weeks) and change after training (30 weeks). Median values and interquartile range are indicated. aWilcoxon signed rank test. bMann-Whitney U-test. NPY, neuropeptide Y.
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