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Table 4 Fatigue versus adipokines, IGF-1 and neuropeptides

From: Exercise and obesity in fibromyalgia: beneficial roles of IGF-1 and resistin?

  

FIQ fatigue

Adiponectin

Leptin

Resistin

Free IGF-1

Total IGF-1

IGFB3

NPY

NGF

MFIGF

r

P

n

0.623

<0.001

48

0.107

0.468

48

-0.074

0.618

48

-0.125

0.398

48

0.024

0.871

48

0.254

0.100

43

0.039

0.801

44

0.150

0.464

26

0.141

0.493

26

FIQ Fatigue

r

P

n

1.000

48

0.143

0.333

48

-0.345

0.016

48

-0.111

0.451

48

-0.032

0.829

48

0.198

0.203

43

0.155

0.315

44

0.004

0.984

26

-0.412

0.037

26

Adiponectin

r

P

n

 

1.000

48

0.032

0.827

48

0.123

0.405

48

-0.200

0.172

48

0.148

0.343

43

-0.143

0.355

44

0.245

0.227

26

-0.151

0.460

26

Leptin

r

P

n

  

1.000

48

0.153

0.300

48

0.131

0.374

48

-0.354

0.020

43

0.082

0.595

44

0.472

0.015

26

0.426

0.030

26

Resistin

r

P

n

   

1.000

48

-0.103

0.486

48

0.036

0.817

43

-0.043

0.782

44

0.023

0.912

26

0.148

0.470

26

Free IGF-1

r

P

n

    

1.000

48

0.366

0.016

43

0.361

0.016

44

0.167

0.414

26

0.401

0.042

26

Total IGF-1

r

P

n

     

1.000

43

0.188

0.250

39

0.085

0.706

22

0.233

0.296

22

IGFB3

r

P

n

      

1.000

44

0.395

0.046

26

0.198

0.332

26

Neuropeptide Y

(NPY)

r

P

n

       

1.000

26

0.340

0.089

26

  1. Correlation between baseline fatigue (FIQ and MFIGF), serum free IGF-1, serum levels of total IGF-1, IGFB3, adipokines and neuropeptides. r, Spearman's correlation coefficient; P, P-value; n, number; MFIGF, Multidimensional Fatigue Inventory subscale of General Fatigue; FIQ, Fibromyalgia Impact Questionnaire; IGF, insulin-like growth factor; IGFB3, insulin-like growth factor-binding protein-3; NGF, nerve growth factor.