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Table 7 Change in fatigue in lean, overweight and obese patients versus change in adipokines, IGF-1 and neuropeptides

From: Exercise and obesity in fibromyalgia: beneficial roles of IGF-1 and resistin?

Lean patients ∆MFIGF
30 wks
∆Adiponectin
30 wks
∆Leptin
30 wks
∆Resistin
30 wks
∆Free IGF-1
30 wks
∆Tot IGF-1
30 wks
∆IGFB3
30 wks
∆NPY
30 wks
∆NGF
30 wks
∆FIQ Fatigue
30 weeks
r
P
n
0.268
0.521
8
0.541
0.210
7
-0.432
0.333
7
-0.685
0.090
7
0.145
0.784
6
0.812
0.05
6
0.086
0.872
6
1.000
2
1.000
2
∆MFIGF
30 weeks
r
P
n
1.000
8
0.275
0.550
7
-0.220
0.635
7
-0.239
0.606
7
0.059
0.912
6
0.706
0.117
6
0.177
0.738
6
1.000
2
1.000
2
Overweight patients ∆MFIGF
30 wks
∆Adiponectin
30 wks
∆Leptin
30 wks
∆Resistin
30 wks
∆Free IGF-1
30 wks
∆Tot IGF-1
30 wks
∆IGFB3
30 wks
∆NPY
30 wks
∆NGF
30 wks
∆FIQ Fatigue
30 wks
r
P
n
0.530
0.008
24
-0.219
0.315
23
-0.099
0.654
23
0.270
0.213
23
-0.021
0.924
22
0.213
0.380
19
0.260
0.232
23
0.394
0.164
14
-0.475
0.086
14
∆MFIGF
30 wks
r
P
n
1.000
24
-0.089
0.685
23
0.127
0.562
23
-0.265
0.222
23
-0.233
0.297
22
-0.012
0.962
19
0.104
0.635
23
0.384
0.176
14
-0.047
0.874
14
Obese patients ∆MFIGF
30 wks
∆Adiponectin
30 wks
∆Leptin
30 wks
∆Resistin
30 wks
∆Free IGF-1
30 wks
∆Tot IGF-1
30 wks
∆IGFB3
30 wks
∆NPY
30 wks
∆NGF
30 wks
∆FIQ Fatigue
30 wks
r
P
n
0.283
0.373
12
-0.753
0.019
9
0.084
0.831
9
-0.326
0.391
9
-0.711
0.032
9
-0.261
0.498
9
0.072
0.878
7
0.154
0.805
5
-0.205
0.741
5
∆MFIGF
30 wks
r
P
n
1.000
12
-0.210
0.587
9
0.647
0.060
9
-0.815
0.007
9
-0.025
0.949
9
-0.418
0.263
9
0.786
0.036
7
-0.900
0.037
5
0.500
0.391
5
  1. Correlation after 30 weeks between change (∆) in fatigue (∆FIQ and ∆MFIGF) and change in serum free IGF-1, serum levels of IGFB3, adipokines and neuropeptides in lean patients, overweight and obese patients. r, Spearman's correlation coefficient; P, P-value; n, number; FIQ, Fibromyalgia Impact Questionnaire; MFIGF, Multidimensional Fatigue Inventory subscale of General Fatigue; IGF, insulin-like growth factor; IGFB3, insulin-like growth factor-binding protein-3; NGF, nerve growth factor; NPY, neuropeptide Y.
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