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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Interleukin 37 limits monosodium urate crystal-induced innate immune responses in human and murine models of gout

Fig. 1

Expression of IL-37 in patients with gouty arthritis. a H&E staining of synovial tissue from a person with active gouty arthritis. b Immunohistochemical staining of IL-37 in the same synovial tissue. c H&E staining of subcutaneous tophus from patients with chronic tophaceous gout. d Immunohistochemical staining of IL-37 (arrow) in the same subcutaneous tophus. e Concentration of IL-37 in serum from patients with acute gout (AG, n = 16) or non-acute gout (NAG, n = 15), and from healthy controls (HC, n = 18), and in synovial fliud (SF) from patients with acute gout (n = 5); *P < 0.05,**P < 0.01,***P < 0.001. f Expression of pro-IL-37 mRNA in the peripheral blood mononuclear cells (PBMCs) from patients with gout (AG, n = 10, NAG, n = 10); **P < 0.01

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Arthritis Research & Therapy

ISSN: 1478-6362

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