Table 2 Fifty most significantly dysregulated genes in articular cartilage of ColIITgcog DMM compared to +/+ DMM mice
Gene name | Fold change | p adj |
|---|---|---|
Enpp2 | 3.80 | 7.729E−24 |
Apobr | − 5.38 | 1.581E−18 |
Gas1 | 3.90 | 1.581E−18 |
Serpina3n | 5.76 | 3.413E−16 |
Chil1 | 3.32 | 9.585E−15 |
Ltf | − 5.29 | 1.778E−14 |
Ighg2b | − 13.55 | 4.240E−13 |
Fam111a | − 5.01 | 5.242E−13 |
Tnfrsf11b | 2.07 | 1.495E−12 |
Lyz2 | − 3.05 | 2.941E−12 |
Mgp | 3.22 | 3.442E−12 |
Itga2b | − 7.20 | 1.080E−11 |
Lox | 2.43 | 7.576E−11 |
Cpq | 2.78 | 1.069E−10 |
Eno2 | 6.51 | 2.247E−10 |
Aph1b | − 9.03 | 8.851E−10 |
Scara3 | 2.37 | 1.834E−09 |
Camp | − 4.11 | 2.179E−09 |
Rcan1 | 3.15 | 5.282E−09 |
Alox5 | − 9.00 | 6.821E−09 |
Sema3c | 3.29 | 1.006E−08 |
Pabpc1 | − 1.83 | 2.472E−08 |
Pcsk5 | 2.35 | 2.829E−08 |
Hells | − 5.99 | 6.300E−08 |
Hbb-bt | − 4.42 | 1.544E−07 |
2810474O19Rik | − 2.22 | 1.727E−07 |
Magt1 | 2.26 | 2.385E−07 |
Gda | − 3.70 | 2.393E−07 |
S100a8 | − 3.75 | 4.021E−07 |
Plekha2 | − 2.69 | 4.102E−07 |
Clmp | 2.27 | 4.102E−07 |
Pkd2 | 2.19 | 4.102E−07 |
Dcn | 2.07 | 4.102E−07 |
Ank2 | 2.29 | 1.365E−06 |
Fkbp9 | 1.84 | 1.590E−06 |
Rps2-ps13 | − 6.65 | 1.822E−06 |
Tm4sf1 | 1.65 | 2.902E−06 |
Vill | − 5.60 | 3.656E−06 |
Ncf1 | − 3.48 | 3.656E−06 |
Cenpf | − 3.95 | 4.238E−06 |
Mcfd2 | 2.69 | 4.270E−06 |
Ccdc125 | − 6.25 | 4.462E−06 |
Spp1 | 2.95 | 4.873E−06 |
Celf2 | − 3.53 | 5.489E−06 |
Serpina3g | 5.40 | 5.552E−06 |
Aqp1 | − 2.45 | 5.886E−06 |
Lta4h | − 3.62 | 6.559E−06 |
Mki67 | − 3.47 | 8.515E−06 |
Hist1h2ai | − 2.85 | 8.954E−06 |
Tmsb4x | − 2.51 | 9.833E−06 |