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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Correlation of peripheral CD4+GranzB+CTLs with disease severity in patients with primary Sjögren’s syndrome

Fig. 4

Expression of CD4+GranzB+CTLs in the labial salivary glands (LSGs). A-1 Immunofluorescence staining of CD4 (green), GranzB (red), and DAPI (blue) in LSGs for a healthy control (HC), a pSS patient with non-expression of CD4+GranzB+CTLs (LGS-GranzB(−)), and a pSS patient with high expression of CD4+GranzB+CTLs (LGS-GranzB(+)). Scale bars, 50μm. A-2 The image in the white box of A-1 at high power. Scale bars, 20 μm. B Comparison of CD4+GranzB+CTLs% in the peripheral blood in HC (n = 13), LGS-GranzB(−) (n = 22), and LGS-GranzB(+) groups (n = 7). Error bars represent SD. p values are based on Student’s t-test. C Comparison of ESSDAI in the LGS-GranzB(−) (n = 22) and LGS-GranzB(+) groups (n = 7). Error bars represent SD. p values are based on Student’s t-test. ***p < 0.001, **p < 0.01. ns, no significance

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Arthritis Research & Therapy

ISSN: 1478-6362

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