Skip to main content

Table 1 Demographic data and clinical characteristics among septic patients with and without SLE

From: Impact of systemic lupus erythematosus on the 5-year survival of critically ill septic patients

 

SLE

Non-SLE

p value

(n = 513)

(n = 2052)

Age, years

48.8 ± 16.3

48.8 ± 16.3

1

Gender

  

1

 Female

442 (86.2)

1768 (86.2)

 

 Male

71 (13.8)

284 (13.8)

 

Urbanisation levels

  

< 0.001

 Urban

164 (32.0)

475 (23.1)

 

 Suburban

221 (43.1)

947 (46.2)

 

 Rural

128 (25.0)

630 (30.7)

 

Low insured incomea

243 (47.4)

1141 (55.6)

< 0.001

CCI without renal disease, mean ± SD

2.9 ± 1.7

2.4 ± 2.6

< 0.001

CCI without renal disease, group

  

< 0.001

 0

4 (0.8)

608 (29.6)

 

 1–3

359 (70.0)

930 (45.3)

 

 > 3

150 (29.2)

514 (25.0)

 

Recent hospitalised infectionb

78 (15.2)

199 (9.7)

< 0.001

Medications

   

Glucocorticoid use

506 (98.6)

1606 (78.3)

< 0.001

Glucocorticoid dosage, mg/dayc

47.9 ± 85.1

15.7 ± 40.2

< 0.001

Glucocorticoid dosage groupc

  

< 0.001

 0 mg/day

7 (1.4)

447 (21.8)

 

 0-5 mg/day

27 (5.3)

678 (33.0)

 

 ≥ 5 mg/day

479 (93.4)

927 (45.2)

 

DMARD

   

 Methotrexate

20 (3.9)

45 (2.2)

0.032

 Sulfasalazine

10 (1.9)

14 (0.7)

0.014

 Hydroxychloroquine

331 (64.5)

36 (1.8)

< 0.001

 Immunosuppressantsd

294 (57.3)

98 (4.8)

< 0.001

  1. aInsured income lower than median income (21,900 New Taiwan dollars). bWithin 3 months prior to index admission. cPrednisolone equivalent. dCyclophosphamide, azathioprine, cyclosporine, mycophenolate, and mycophenolic. Abbreviations: SLE Systemic lupus erythematosus, CCI Charlson comorbidity index, DMARD Disease-modifying antirheumatic drug