Fig. 2
Analysis of differential variable positions (DVPs) identified with iEVORA algorithm between AS patients and HCs. A Volcano plot of the effect size [log2 (variation ratio of AS compared to HCs)] vs. [-log10 (p value)]. Red dots and blue dots denote the hypervariable probes (n= 974) and the hypovariable probes (n=74) with the p value of t test below 0.05 and FDR of Bartlett’s test below 0.001. B, C The methylation level (β values) of the two positions displaying methylation variability in the AS case and control samples