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Table 3 Indicator genera analysis of fecal and oral microbial communities for healthy and diseased individuals. Potential HACEK-group members are highlighted in bold face and genera marked with “*” show repeated associations

From: Analysis of the fecal and oral microbiota in chronic recurrent multifocal osteomyelitis

Data

Factor

Genus classification (RDP16)

Assoc.

IndVal.g

P-Value

PFDR

Stool

Disease

Faecalibacterium

CRMO

0.79720

0.00250

0.16123

Barnesiella*

Healthy

0.79559

0.03250

0.46579

Coprobacter

 

0.71171

0.02110

0.46435

Porphyromonadaceae uncl.

 

0.69602

0.02880

0.46435

Paraprevotella

 

0.67131

0.00200

0.16123

Christensenella

 

0.57721

0.01070

0.34504

Oscillibacter*

 

0.80668

0.04010

0.46693

Holdemania

 

0.79469

0.00980

0.34504

Betaproteobacteria uncl.

 

0.53721

0.02720

0.46435

Bilophila

 

0.75734

0.02600

0.46435

Acinetobacter

 

0.44721

0.04220

0.46693

Relapse

Clostridium XVIII

Yes

0.84863

0.02530

0.45555

Barnesiella*

No

0.86570

0.02210

0.45555

Odoribacter

 

0.85980

0.02680

0.45555

Alistipes

 

0.91034

0.00220

0.22438

Anaerovorax

 

0.88385

0.00710

0.24138

Oscillibacter*

 

0.89888

0.00620

0.24138

Saliva

Disease

Actinomyces

CRMO

0.83715

0.04220

0.40217

Actinomycetales uncl.

 

0.75191

0.03880

0.40217

Corynebacteriaceae uncl.

 

0.52099

0.03290

0.40217

Corynebacterium

 

0.93276

0.00510

0.15936

Propionibacteriaceae uncl.

 

0.84285

0.00020

0.01250

Leptotrichia

 

0.89057

0.00990

0.18212

Lautropia

 

0.93432

0.01970

0.30778

Eikenella

 

0.81943

0.00230

0.09582

Kingella

 

0.91866

0.00010

0.01250

Campylobacter

 

0.87207

0.01020

0.18212

Cardiobacterium

 

0.84092

0.00760

0.18212

Granulicatella

Healthy

0.82050

0.02750

0.38191

Veillonella

 

0.83492

0.04830

0.40217

Relapse

-

-

-

-

-