Table 1 General characteristics of anti-CCP+ low (> 1 to < 3x ULN) and high level (> 3x ULN) individuals (SD = standard deviation)
Overall anti-CCP+ (n = 151) | Anti-CCP+ low level (n = 53) | Anti-CCP+ high level (n = 98) | P value | |
|---|---|---|---|---|
Sex, female n (%) | 93 (61.6) | 38 (71.7) | 55 (56.1) | 0.060 |
Mean age (SD; range) in years | 52 (15.2; 19–83) | 46 (15.3; 18–77) | 55 (14.2; 25–83) | 0.001 |
Mean follow-up (SD; range) in weeks | 105 (121.8; 2–560) | 133 (117.2; 6–527) | 91 (122.1; 2–560) | 0.041 |
Family history of RA, n (%) | 76 (53.1) | 28 (57.1) | 48 (51.1) | 0.489 |
Smoking status, n (%) | Never 53 (37.1) Ever smoked 90 (62.9) | Never 20 (40.0) Ever smoked 30 (60.0) | Never 33 (35.5) Ever smoked 60 (64.5) | 0.590 |
• Never n (%) | 53 (37.1) | 20 (40.0) | 33 (35.5) | |
• Previous n (%) | 65 (45.5) | 21 (42.0) | 44 (47.3) | |
• Current n (%) | 25 (17.5) | 9 (18.0) | 16 (17.2) | |
Progression to IA, n (%) | 68 (45%) | 7 (13%) | 61 (62%) | < 0.001 |