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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Angiopoietin-2/-1 ratios and MMP-3 levels as an early warning sign for the presence of giant cell arteritis in patients with polymyalgia rheumatica

Fig. 1

ROC curves for biomarker levels in overlapping GCA/PMR patients as compared to isolated PMR patients. Shown are ROC curves in solid black for the Aarhus cohort and dotted blue for the GPS cohort and the corresponding values of the area under the curve (AUC). Optimal sensitivity (Sens), specificity (Spec) and cut-off values were calculated according to the Youden index. In the Aarhus cohort, overlapping GCA/PMR N=13 and isolated PMR N=25. In the GPS cohort, N=11 for overlapping GCA/PMR and N=39 for isolated PMR, except for angpt-2/angpt-1 ratio (N=10 and 29, respectively) and MMP-3 (N=10 and 35, respectively). ROC receiver operating characteristic

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