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Table 3 Cranial and systemic symptoms differ in overlapping GCA/PMR patients when compared to isolated PMR patients

From: Angiopoietin-2/-1 ratios and MMP-3 levels as an early warning sign for the presence of giant cell arteritis in patients with polymyalgia rheumatica

 

Aarhus cohort

Groningen GPS cohort

GCA/PMR overlap

Isolated PMR

p-value

GCA/PMR overlap

Isolated PMR

p-value

N

 

13

25

 

11

39

 

New headache

%

54

12

0.02

45

23

ns

Jaw/tongue claudication

%

23

0

0.03

15

13

ns

Abnormal temporal artery

%

31

0

0.0097

8

8

ns

Visual symptoms

%

0

0

ns

23

0

0.008

Scalp tenderness

%

15

8

ns

15

10

ns

Limb claudication

%

31

8

ns

23

15

ns

Fever

%

54

32

ns

31

15

ns

Weight loss

%

92

44

0.005

85

49

0.0016

Night sweats

%

75

36

0.04

46

38

ns

Malaise

%

100

92

ns

62

85

ns

  1. In both cohorts, the incidence of symptoms was compared between the two patient populations using Fisher’s exact test. The only symptom that is significantly more common in overlapping GCA/PMR patients of both cohorts is weight loss. Of note, weight loss is scored as >2 kg in the GPS cohort and >3 kg in the Aarhus cohort
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Arthritis Research & Therapy

ISSN: 1478-6362

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