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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Impaired activation of STAT5 upon IL-2 stimulation in Tregs and elevated sIL-2R in Sjögren’s syndrome

Fig. 2

Reduced pSTAT5 upon IL-2 stimulation associated with Sjögren’s syndrome. A Patients with SS had significantly lower frequency of pSTAT5+ Tregs upon IL-2 stimulation (left panel) and higher pSTAT5+ Tregs at baseline (right panel). B The difference in pSTAT5+ Tregs between baseline and IL-2 stimulation was significantly lower in patients with SS. C The delta in pSTAT5+ Tregs was lowest in patients with non-severe SS. (Mann-Whitney U test was used in the comparison between the different groups. *p≤0.05, **p≤0.01, ***p≤0.001 and ***p≤0.0001)

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Arthritis Research & Therapy

ISSN: 1478-6362

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