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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Tissue catabolism and donor-specific dexamethasone response in a human osteochondral model of post-traumatic osteoarthritis

Fig. 6

Partial least squares regression of Dex attenuation of sGAG loss. A. Protein loadings after PLSR of all batch-corrected media proteomic data against the percent of increased sGAG loss caused by IC treatment that was reduced by Dex for each donor. Enriched biological processes were determined with Gene Set Enrichment Analysis. XL: predictor loading values. B. PLSR of only untreated control media against the percent Dex attenuation of increased sGAG loss with IC treatment

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