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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Oral dextran sulfate sodium administration induces peripheral spondyloarthritis features in SKG mice accompanied by intestinal bacterial translocation and systemic Th1 and Th17 cell activation

Fig. 4

Oral DSS administration increases the amount of circulating bacterial DNA and the number of common species in the groups. a The concentration of bacterial DNA in whole blood measured by absolute qPCR, 0, 1, 7, and 14 days after oral DSS treatment initiation. Five mice per group were used. Values are presented as mean ± SEM. b The concentration of bacterial DNA measured by qPCR in whole blood after DSS treatment with and without antibiotics. Five mice per group were used. c Venn diagrams showing the number of bacterial species in circulating bacterial DNA on days 0 and 14. Five mice were examined per group. Identical numbers of mice are shown by #. Twenty mice were examined as a whole. d. The Shannon index before and after DSS administration. Five mice were examined per group. Statistical analyses were performed using the Mann-Whitney U test (*P <0.05, **P <0.01)

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