Skip to main content
Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Improved skeletal muscle fatigue resistance in experimental autoimmune myositis mice following high-intensity interval training

Fig. 4

HIIT increases markers of mitochondrial respiration in the skeletal muscle of EAM mice. Citrate synthase (CS) (A) and cytochrome c oxidase (COX) (B) activities in the plantaris muscles from control (CNT) and EAM mice with or without high-intensity interval training (HIIT). Representative western blots illustrating the levels of peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) (C); complex I (CI) subunit (NDUFB8), CII subunit (SDHB), CIII subunit (UQCRC), CIV subunit (MTC01), and CV subunit (ATP5) (E); and adenosine monophosphate deaminase 1 (AMPD1) and dystrophin (G) in the gastrocnemius muscles. The levels of PGC-1α (D), CI-V (F), AMPD1, and dystrophin (H) were normalized to total protein in stain-free images, and the mean in CNT muscles was set to 100%; n = 6 muscles per group. One-way ANOVA with Bonferroni post hoc test was performed. *P < 0.05 vs CNT, #P < 0.05 vs EAM

Back to article page