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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Improved skeletal muscle fatigue resistance in experimental autoimmune myositis mice following high-intensity interval training

Fig. 5

HIIT alleviates the upregulation of ER stress proteins in the gastrocnemius muscle of EAM mice. Representative western blots illustrating the levels of glucose-regulated protein (Grp) 78 (A), Grp94 (B), inositol-requiring transmembrane kinase endoribonuclease-1α (IRE-1α) (E), and PKR-like ER kinase (PERK) (F) of the gastrocnemius muscles in control (CNT) and EAM mice with or without high-intensity interval training (HIIT). Bars showing the mean and SEM levels of these proteins (C, D, G, H). Data were normalized to the total proteins from the stain-free image, and the mean in CNT muscles was set to 100%; n = 5–6 muscles per group. One-way ANOVA with Bonferroni post hoc test was performed. *P < 0.05 vs CNT, #P < 0.05 vs EAM

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