Table 1 Diastolic parameters TTE definition and physiologic implications

Mitral E wave velocity

Peak modal velocity across the mitral valve in early diastole

If high, indicates impaired LV relaxation + elevated LV filling pressures

DT of E wave

Deceleration time of mitral E velocity from peak to the baseline

If low/shortened, impaired LV relaxation or elevated LV filling pressures

Septal e’ wave velocity

Lateral e′ wave velocity

Tissue Doppler-based measure of LV muscle relaxation at septal/lateral aspect of mitral valve annulus, in early diastole

If low, indicates impaired LV relaxation

E/e′

Mitral E wave velocity divided by e′ (averaged from septal/lateral e′)

Corrected for the effect of LV relaxation; If high, indicates elevated LV filling pressures

LA volume index

Left atrial volume indexed to BSA

If high, indicates cumulative effects of elevated LV filling pressures

TR velocity

Peak tricuspid valve regurgitant velocity

Estimation of pulmonary artery systolic pressure; If high, indicates elevated LV filling pressures