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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration

Fig. 1

The BMAL1 expression of NP specimens in human donors, rat NP tissues, and cells. a, b Immunohistochemical staining images and quantification of BMAL1 in human NP tissues from the grade II and grade V groups. We selected 3 random fields in per individual for quantitative analysis (scale bar: 250 μm). n = 3, **P < 0.01. c, d Immunofluorescence staining images and quantification of BMAL1 in human NP tissues from the Grade II and Grade V groups. We selected 3 random fields in per individual for quantitative analysis (scale bar: 125 μm). n = 4, **P < 0.01. e, f Immunofluorescence staining images and quantification of BMAL1 in rat NP tissues from Control and puncture groups cultured 0 days, 7 days, and 14 days (scale bar: 500 μm). n = 3, NS, P>0.01, **P < 0.01. g The mRNA levels of Bmal1 and Clock in control and IL-1β. n = 3, *P<0.05, **P < 0.01

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