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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration

Fig. 5

SFN attenuated the degeneration of rat NP tissues in an organotypic tissue-explant model. The NP tissues were divided into four groups, control, needle-punctured, needle-punctured + 5 μM SFN, and needle-punctured + 10 μM SFN. a Immunofluorescence staining of BMAL1 in rat NP tissues cultured 7 days and 14 days (scale bar: 500 μm). b Immunofluorescence staining of NRF2 in rat NP tissues cultured for 7 days and 14 days (scale bar: 500 μm). c HE and safranin O staining of the rat IVDs cultured for 7 days and 14 days (scale bar: 500 μm)

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Arthritis Research & Therapy

ISSN: 1478-6362

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