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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Levels of extracellular matrix metabolites are associated with changes in Ankylosing Spondylitis Disease Activity Score and MRI inflammation scores in patients with axial spondyloarthritis during TNF inhibitor therapy

Fig. 1

Time course of biomarkers in response to TNF-α inhibitor therapy. A Type I collagen formation, PRO-C1; B type III collagen formation, PRO-C3; C type IV collagen turnover, PRO-C4; D type VI collagen formation, PRO-C6; E type III collagen degradation, C3M; F type IV collagen degradation, C4M; G type VI collagen degradation, C6M; H type VII collagen degradation, C7M; I type X collagen degradation, C10C; J C-reactive metabolite, CRPM; K elastin degradation, EL-NE; L citrullination and degradation of vimentin, VICM; and M C-reactive protein, CRP. Time course is shown as median ± 95% CI. *p<0.05 **p<0.01, ***p<0.001, ****p<0.0001

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