Table 2 Effect of RT on biomarker levels from PRE-XT to POST-XT and FU. Serum samples were collected before RT start (T1), after 3-month supervised RT (T2), and after 6-month home training (T3). The biomarker data were log-transformed, and the difference in biomarker levels from PRE-XT to POST-XT and from PRE-XT to FU was calculated and used as an outcome as a model was fitted to the data using linear mixed models. The difference in biomarker levels was used to calculate p values using probability cumulative analysis on Student’s t-distribution
| Â | T2 | T3 | ||||
|---|---|---|---|---|---|---|
| Â | Percent change from T1 | Percent change from T1 | ||||
| Â | Mean | 95% CI | p-value | Mean | 95% CI | p-value |
High-intensity resistance training | ||||||
Log huARGS | 25.0 | 15.73, 35.11 | <0.0001 | 50.2 | 15.73, 62.28 | <0.0001 |
Log C2M | 27.9 | 18.67, 38.05 | <0.0001 | 42.0 | 31.24, 53.64 | <0.0001 |
Log PRO-C2 | -3.9 | -9.56, 2.16 | 0.203 | 5.7 | -0.83, 12.60 | 0.883 |
Low-intensity resistance training | ||||||
Log huARGS | 8.7 | 0.186, 17.86 | 0.045 | 23.9 | 13.80, 34.90 | <0.0001 |
Log C2M | 17.8 | 8.80, 27.51 | 0.0001 | 54.1 | 41.77, 67.39 | <0.0001 |
Log PRO-C2 | -6.0 | -11.80, 0.24 | 0.059 | 2.6 | -8.88, 4.20 | 0.447 |