Fig. 1
From: STING mediates experimental osteoarthritis and mechanical allodynia in mouse
Upregulation of the cytosolic DNA sensors, IFI204 and STING, in OA-like mouse chondrocytes. A Heat map of cytosolic nucleic acid sensors in chondrocytes treated with IL‐1β (1 ng/ml, 36 h) or infected with 800 MOI of Ad-HIF‐2α or Ad-ZIP8 (36 h). B-E Representative RT-PCR images (B) and relative mRNA levels (C–E) of the indicated molecules in mouse chondrocytes treated with IL-1β or infected with the indicated MOI of Ad-C (control), Ad-HIF-2α, or Ad-ZIP8 for 36 h. Values are presented as mean ± 95% CI, and significance was evaluated by paired t-test (n = 7)