Fig. 4
From: Characterization of miR-335-5p and miR-335-3p in human osteoarthritic tissues
Assessing functional effects of miR-335-5p in knee OA fat pad. A Canonical adipogenesis network generated from Ingenuity Pathway Analysis software, shaded symbols = predicted miR-335-5p targets. B miRNA expression changes following miR-335-5p inhibitor versus control inhibitor treatment and miR-335-5p mimic versus control mimic treatment in late-stage knee OA fat pad explants used for Oil-Red-O staining (n = 3). C Quantification of Oil-Red-O staining in miR-335-5p inhibitor or mimic treated explants relative to control inhibitor or mimic, respectively (n = 3). -5p = miR-335-5p; inh. = inhibitor; mim. = mimic; FC, fold-change; bars = 95% CI; *p < 0.05. D Representative images of late-stage knee OA fat pad sections corresponding to each group in panel C; red = Oil-Red-O stain, magnification = 10 × , scale bar = 100 µm