Fig. 2

NDG are more activated during SLE compared to a healthy pregnancy. A Representative flow cytometry plots from SLE and HC that illustrate the gating strategy for proportions of NDG that have shed CD62L and NDG that express CD10, respectively. Proportions of NDG that have shed CD62L (B) in the first, second, and third trimesters (T1, T2, and T3) compared to late postpartum in women with SLE, and (C) in SLE compared to HC pregnancies (combined data from trimester one to three). D TruCount gating strategy for granulocytes in SLE and healthy women. E Total granulocyte counts in blood in the first, second, and third trimesters compared to late postpartum in women with SLE. F Total granulocyte counts in the first, second, and third trimesters in pregnant women with SLE compared to pregnant healthy women. *p ≤ 0.05, **p < 0.01 and ****p < 0.0001, B and E Kruskal-Wallis followed by Dunn’s multiple comparison test and C and F Mann-Whitney U test. Illustration created in BioRender.com