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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Aberrant mechanical loading induces annulus fibrosus cells apoptosis in intervertebral disc degeneration via mechanosensitive ion channel Piezo1

Fig. 5

CMS affected the Calcium signaling pathway in AFCs. a Heatmap of differentially expressed genes in AFCs treatment with Lv-Ctrl and Lv-Piezo1 under CMS (n = 4). b Volcano map of differentially expressed genes in AFCs treatment with Lv-Ctrl and Lv-Piezo1 under CMS. c GO pathway analysis of differentially expressed genes in AFCs treatment with Lv-Ctrl and Lv-Piezo1 under CMS. d KEGG pathway analysis of differentially expressed genes in AFCs treatment with Lv-Ctrl and Lv-Piezo1 under CMS. e GSEA analysis of Calcium signaling pathway (KEGG pathway number: RNO04020) in AFCs treatment with Lv-Ctrl and Lv-Piezo1 under CMS

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