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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Renal interferon-inducible protein 16 expression is associated with disease activity and prognosis in lupus nephritis

Fig. 1

Bioinformatics analysis to identify key biomarkers in LN. A Volcano plots of the differentially expressed genes (DEGs). Red: genes upregulated in LN; green: genes downregulated in LN. B GO functional enrichment for the DEGs. C KEGG pathway enrichment for the DEGs. D Candidate diagnostic marker genes identified using LASSO logistic regression. E Candidate diagnostic marker genes identified using SVM-RFE. F Candidate diagnostic marker genes identified using RF algorithm. G Venn diagram of candidate diagnostic genes identified using three algorithms. H The difference in expression of IFI16 in training set. I  ROC curve for IFI16 using the training set. J The difference in expression of IFI16 in validation set. K ROC curve for IFI16 using validation set

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Arthritis Research & Therapy

ISSN: 1478-6362

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