Fig. 9
From: Sirt3 improves monosodium urate crystal-induced inflammation by suppressing Acod1 expression
Sirt3 deficiency exacerbated MSU crystal-induced inflammation in vivo. a Representative plots of migrated leukocytes (CD45+) and neutrophils (CD11b+Gr-1.+) in the peritoneal fluid were detected by FCM. The number of migrated leukocytes and neutrophils were quantified and compared among the groups on the right. b The levels of IL-1β and CCL2 in the peritoneal fluid were detected by ELISA. c Paw swelling index. d Representative microscopic images of mouse paw sections stained with HE (magnification 20 × 10). n = 5 mice for each group. *P < 0.05