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Fig. 7 | Arthritis Research & Therapy

Fig. 7

From: Integrative bioinformatics analysis and experimental validation of key biomarkers for risk stratification in primary biliary cholangitis

Fig. 7

Verification of four hub genes in PBC model mice. A Histological features of the 12–14 weeks liver of wild types and dnTGF-β RII mice. The typical pathology was designated by the black arrow, characterized by a heavy infiltration of lymphocytes in the portal areas of the liver. B–E The expression of TXNIP, CD44, ENTPD1, and PDGFRB was significantly upregulated in dnTGF-β RII mice compared with wild-type mice. *P < 0.05, ***P < 0.001

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