Table 2 Multivariate analysis assessing the 10-year mTSS progression and 10-year HAQ-DI: final models using SDAI as disease activity score

Ten-year mTSS progression

Centre

16.5

NS

Baseline erosions

59.9

 < 0.0001

SDAI group

8.1

0.01

SDAI group* time

4.5

NS

SDAI*intercept

0.6

NS

ACPA

0.4

NS

ACPA*time

30.6

 < 0.0001

ACPA*intercept

7.3

0.006

Time

1.5

NS

Intercept

1.1

NS

Results of the contrast method

Final model:

LDA versus remission

3.2

 < 0.01

MDA or HDA versus remission

4.5

 < 0.0001

MDA or HDA versus LDA

2.1

 < 0.05

Ten-year HAQ-DI

RF

8.3

 < 0.01

bDMARD

11.9

 < 0.001

SDAI group

57.5

 < 0.0001

SDAI group*time

98.9

 < 0.0001

SDAI group*intercept

72.1

 < 0.0001

DMARDs use

0.04

NS

DMARDs use*time

6.1

 < 0.05

DMARDs use*intercept

7.5

 < 0.01

Methotrexate use

0.1

NS

Methotrexate*time

1.7

NS

Corticosteroids use

3.9

 < 0.05

Corticosteroids use*time

6.7

 <  < 0.01

Corticosteroids use*intercept

5.8

 < 0.05

Time

12.7

 < 0.001

Intercept

9.5

 < 0.01

Results of the contrast method

Final model:

LDA versus remission

5.2

 < 0.0001

MDA or HDA versus remission

9.0

 < 0.0001

MDA or HDA versus LDA

5.6

 < 0.0001