RE meta-regression model | β | pβ | τ2 (95% CI) | R2 |
---|---|---|---|---|
Without factor | - | - | 2.23 (1.18, 7.61) | - |
Previously associated factors | ||||
AF ancestry (%)a | 0.25 | 0.032 | 1.56 (0.89, 6.43) | 0.300 |
Anti-CCP (%) | − 0.06 | 0.8 | 2.21 (1.26, 9.09) | 0.009 |
Women (%) | − 0.81 | 0.0070 | 1.32 (0.75, 5.53) | 0.408 |
Smokers (%) | 0.61 | 0.10 | 1.77 (1.01, 7.36) | 0.206 |
Age (years) | 0.03 | 0.6 | 2.18 (1.25, 8.99) | 0.022 |
Time since diagnosis (y) | 0.04 | 0.7 | 2.27 (1.28, 10.52) | 0.000 |
Potential confounders | ||||
Percentile | − 0.03 | 0.5 | 2.15 (1.23, 8.81) | 0.036 |
Military (yes) | 1.83 | 0.032 | 1.56 (0.89, 6.44) | 0.300 |
Site (N/O)b | 2.03 | 0.0044 | 1.27 (0.72, 5.27) | 0.431 |
Site (L/O’)c | − 0.43 | 0.6 | 2.18 (1.25, 8.99) | 0.022 |
Best forward selection modeld | ||||
Site (N/O)b | 2.03 | 0.0044 | 1.27 (0.72, 5.27) | 0.430 |
Best backward elimination modeld | ||||
AF ancestry (%) | 0.35 | 4.1 × 10−6 | 0.58 (0.35, 3.12) | 0.740 |
Smokers (%) | 0.94 | 2.7 × 10−5 |