From: Systemic sclerosis and risk of bronchiectasis: a nationwide longitudinal cohort study
 | Total (N = 29,070) | Systemic sclerosis cohort (n = 4845) | Matched cohort (n = 24,225) | P value |
---|---|---|---|---|
Male sex | 4422 (15.2) | 737 (15.2) | 3685 (15.2) | > 0.999 |
Age, years | 53.5 ± 12.6 | 53.4 ± 12.6 | 53.5 ± 12.6 | > 0.999 |
 20–39 | 4050 (13.9) | 675 (13.9) | 3375 (13.9) |  |
 40–64 | 19,338 (66.5) | 3223 (66.5) | 16,115 (66.5) |  |
 ≥ 65 | 5682 (19.6) | 947 (19.6) | 4735 (19.6) |  |
Extra-pulmonary comorbidities | ||||
 Diabetes mellitus | 2355 (8.1) | 389 (8.0) | 1966 (8.1) | 0.840 |
 Hypertension | 8411 (28.9) | 2562 (52.9) | 5849 (24.1) | < 0.001 |
 Dyslipidemia | 4836 (16.6) | 922 (19.0) | 3914 (16.2) | < 0.001 |
 ESRD | 88 (0.3) | 35 (0.7) | 53 (0.2) | < 0.001 |
 IHD | 1991 (6.8) | 720 (14.7) | 1271 (5.3) | < 0.001 |
 CHF | 539 (1.8) | 231 (4.8) | 308 (1.3) | < 0.001 |
Pulmonary comorbidities | ||||
 COPD | 2516 (8.6) | 959 (19.8) | 1557 (6.4) | < 0.001 |
 Asthma | 3341 (11.5) | 901 (18.6) | 2440 (10.1) | < 0.001 |
 Previous pulmonary tuberculosis | 52 (0.2) | 24 (0.5) | 28 (0.1) | < 0.001 |
CTDs other than systemic sclerosis | 558 (1.9) | 472 (9.7) | 86 (0.4) | < 0.001 |
 Rheumatoid arthritis | 200 (0.7) | 127 (2.6) | 73 (0.3) | < 0.001 |
 Systemic lupus erythematous | 246 (0.8) | 234 (4.8) | 12 (0.1) | < 0.001 |
 Dermatomyositis | 27 (0.1) | 27 (0.6) | 0 (0) | < 0.001 |
 Mixed connective tissue disease | 112 (0.4) | 112 (2.3) | 0 (0) | < 0.001 |
 Polymyalgia rheumatica | 2 (0.01) | 1 (0.02) | 1 (0) | 0.206 |