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Table 2 Intima-media thickness, plaque score, and pulse wave velocity changes at Week 156

From: Long-term effects of abatacept on atherosclerosis and arthritis in older vs. younger patients with rheumatoid arthritis: 3-year results of a prospective, multicenter, observational study

 

Abatacept

(AY + AO)

csDMARDs

(CY + CO)

P value

Mean intima-media thickness of common carotid artery

 Left

0.022 ± 0.115

0.031 ± 0.116

0.6525

 Right

0.019 ± 0.125

0.034 ± 0.126

0.5163

Max intima-media thickness of common carotid artery, bulbus, bifurcation, and internal carotid artery

 Left

0.008 ± 0.149

0.020 ± 0.215

0.7021

 Right

0.003 ± 0.208

0.018 ± 0.203

0.6817

Plaque score

-0.446 ± 1.662

0.227 ± 1.915

0.0544

Pulse wave velocity

   

 Left

38.9 ± 384.5

73.0 ± 357.5

0.6092

 Right

60.1 ± 242.1

32.3 ± 196.8

0.4868

  1. Results are reported as change of the measured value compared with the baseline value. Abbreviations: AO: older patients taking abatacept; AY: younger patients taking abatacept; CO: older patients taking conventional synthetic disease-modifying antirheumatic drugs; csDMARDs: conventional synthetic disease-modifying antirheumatic drugs; CY: younger patients taking conventional synthetic disease-modifying antirheumatic drugs