Table 4 Summary of adverse events over 156 weeks

Infection

3 (5.8)

9 (12.3)

2 (4.0)

 Pneumonia

1 (1.9)

4 (5.5)

2 (4.0)

 Pulmonary Mycobacterium

 avium complex infection

2 (3.8)

1 (2.0)

 Herpes zoster

2 (2.7)

 Cellulitis

1 (1.4)

 Septic arthritis

1 (1.4)

 Periodontal disease

1 (1.4)

Malignancy

1 (1.9)

6 (8.2)

3 (6.0)

 Lung cancer

2 (2.7)

1 (2.0)

 Breast tumor

1 (1.4)

1 (2.0)

 Lymphadenopathy

1 (1.4)

1 (2.0)

 Prostate cancer

1 (1.4)

 Bladder cancer

1 (1.4)

 Subcutaneous tumor

1 (1.9)

Others

 Bone fracture

3 (4.1)

2 (4.9)

 Joint surgery

2 (2.7)

3 (6.0)

 Diabetes mellitus

2 (4.0)

 Heart failure

2 (4.0)

 Interstitial pneumonia

1 (1.4)

 Hyponatremia

1 (2.0)

 Hypothyroidism

1 (1.4)

 Gallstones

1 (1.9)

 Retinal detachment

1 (2.0)

 Hypersensitivity

1 (1.9)

 Subdural hematoma

1 (2.0)

 Hydrocephalus

1 (2.0)

Death

1 (2.0)

(due to traffic accident)