Skip to main content
  • Retraction Note
  • Open access
  • Published:

Retraction Note: Combined effect of genetic background and gender in a mouse model of bleomycin-induced skin fibrosis

The Original Article was published on 30 May 2015

Retraction Note: Arthritis Res Ther 17, 145 (2015)

https://0-doi-org.brum.beds.ac.uk/10.1186/s13075-015-0659-5

The Editors-in-Chief has retracted this article because after the publication of the article concerns were raised about image overlap. Further investigation by the Publisher found the following concerns to be valid.

  • Partial image overlap between Fig. 1A (upper-left panel, NaCl- BALB/c male mouse) and Fig. 2A (upper-left panel, NaCl—BALB/c female mouse)

  • Partial overlap between Fig. 1A (upper-right panel, NaCl- DBA/2 male mouse) and Fig. 2A (upper-right panel, NaCl-DBA/2 female mouse).

  • Partial image overlap between Fig. 2A (upper-right panel, NaCl-DBA/2) with Fig. 6A (left panel, NaCl)

  • Partial image overlap in Fig. 2A (lower-middle panel, Bleomycin- C57BL/6) with Fig. 5A (upper-right panel, NaCl + Control mAb) of [1].

  • Partial image overlap in Fig. 3D (lower-middle panel, Bleomycin C57BL6/2) with Fig. 6B (lower-right panel, KLH BLM) of [2].

The authors provided the raw data for validation. However, further checks by the Publisher identified some differences between the raw data and the figures, as well as overlap in raw images. The authors were unable to provide ethical approval for experiments involving Balb/c mice strain. The Editors-in-Chief therefore no longer has confidence in the presented data.

Nadine Ruzehaji, Muriel Elhai, Jerome Avouac, Camelia Frantz, Joerg H. Distler and Yannick Allanore agree to this retraction. Maxime Frechet has not responded to any correspondence from the editor/publisher about this retraction. The editor was not able to obtain a current email address for Barbara Ruiz.

References

  1. Elhai M, Avouac J, Maria A, Ruzehaji N, Amiar O, Ruiz B, Brahiti H, Ponsoye M, Fréchet M, Burgevin A, Pezet S, Sadoine J, Guilbert T, Nicco C, Akiba H, Heissmeyer V, Subramaniam A, Resnick R, Molberg Ø, . . . Allanore Y. OX40L blockade protects against inflammation-driven fibrosis. Proc Natl Acad Sci. 2016; 113(27): E3901-E3910. https://0-doi-org.brum.beds.ac.uk/10.1073/pnas.1523512113.

  2. Desallais L, Avouac J, Fréchet M, et al. Targeting IL-6 by both passive and active immunization strategies prevents bleomycin-induced skin fibrosis. Arthritis Res Ther. 2014;16:R157. https://0-doi-org.brum.beds.ac.uk/10.1186/ar4672.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Nadira Ruzehaji.

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ruzehaji, N., Avouac, J., Elhai, M. et al. Retraction Note: Combined effect of genetic background and gender in a mouse model of bleomycin-induced skin fibrosis. Arthritis Res Ther 25, 218 (2023). https://0-doi-org.brum.beds.ac.uk/10.1186/s13075-023-03211-7

Download citation

  • Published:

  • DOI: https://0-doi-org.brum.beds.ac.uk/10.1186/s13075-023-03211-7